Budget impact analysis of pasireotide in the treatment of agromegaly patients from the italian national health service perspective

Authors

  • Francesco Saverio Mennini Economic Evaluation and HTA (CEIS- EEHTA). Faculty of Economics, University of Rome “Tor Vergata”, Italy. Institute for Leadership and Management in Health - Kingston University London, London, UK
  • Andrea Marcellusi National Research Council (CNR), Institute for Research on Population and Social Policies (IRPPS)
  • Fabio Palazzo National Research Council (CNR), Institute for Research on Population and Social Policies (IRPPS).
  • Giampiero Favato Institute for Leadership and Management in Health - Kingston University London, London, UK
  • Raffaella Viti Economic Evaluation and HTA (CEIS- EEHTA). Faculty of Economics, University of Rome “Tor Vergata”, Italy.
  • Chiara Bini Economic Evaluation and HTA (CEIS- EEHTA). Faculty of Economics, University of Rome “Tor Vergata”, Italy.
  • Pietro Maffei Azienda Ospedaliera di Padova, Clinica Medica 3^, DIMED
  • Rosario Pivonello Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli

DOI:

https://doi.org/10.14600/irpps_wps.101.2017

Keywords:

Health Technology Assessment, Budget Impact, Acromegaly, Signifor

Abstract

Background: The objective of this study was to estimate the economic impact, from the perspective of the National Health Service (NHS), of pasireotide in the treatment of adult patients with acromegaly. Methods:. The epidemiological and cost data for Budget Impact (BI) implementation were obtained through a systematic review of the literature. BI were estimated comparing a a scenario with pasireotide and a scenario without from the NHS perspective. A deterministic sensitivity analysis (DSA) and a BI possible value with pay-off method were performed. Results: The model estimated a total of 2,314 patients with acromegaly with a second-line drug in Italy. The introduction of pasireotide for the treatment of acromegaly reduce cost for € 662,095 in the 5 years considered. DSA and pay-off demonstrate the robustness of the results. Conclusions: The introduction on the market of pasireotide reduce real costs from the NHS perspective.

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Published

2017-10-25

How to Cite

Mennini, F. S., Marcellusi, A., Palazzo, F., Favato, G., Viti, R., Bini, C., Maffei, P., & Pivonello, R. (2017). Budget impact analysis of pasireotide in the treatment of agromegaly patients from the italian national health service perspective. IRPPS Working Papers, 1–30. https://doi.org/10.14600/irpps_wps.101.2017

Issue

IRPPS WPs pubblicati nel 2017

Section

Working Papers

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